Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8035890 | 1.00 | GRIK1 (0.45) | GRIK1GRIK2EPHX1DPP4FAP | |
| Lysine SCHEMBL8041475 | 0.88 | GSR (0.42) | GRIK1GRIK2EPHX1DPP4FAP | |
| Lysine SCHEMBL8041477 | 0.88 | GSR (0.42) | GRIK1GRIK2EPHX1DPP4FAP | |
| Cyclohexylamine SCHEMBL8037502 | 0.88 | TSHR (0.42) | GRIK1GRIK2EPHX1DPP4FAP | |
| Cyclohexylamine SCHEMBL8037499 | 0.88 | TSHR (0.42) | GRIK1GRIK2EPHX1DPP4FAP | |
| Cyclohexylamine SCHEMBL7801498 | 0.87 | NPC1 (0.41) | GRIK1GRIK2EPHX1NPC1RAB9A | |
| 4-Hydroxybenzaldehyde SCHEMBL8037281 | 0.85 | ALDH5A1 (0.41) | GRIK1GRIK2NPC1RAB9AALDH1A1 | |
| 4-Hydroxybenzaldehyde SCHEMBL8037276 | 0.85 | ALDH5A1 (0.41) | GRIK1GRIK2NPC1RAB9AALDH1A1 | |
| Benzaldehyde SCHEMBL8035694 | 0.85 | KIF11 (0.42) | GRIK1GRIK2ALDH1A1TRPM8PKM | |
| Cyclohexylamine SCHEMBL8037696 | 0.84 | GRIK1 (0.41) | GRIK1GRIK2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |