Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8037502 | 1.00 | TSHR (0.42) | TSHREPHX1KMT2AGRM4DPP7 | |
| Lysine SCHEMBL8025651 | 0.89 | GRM4 (0.41) | TSHREPHX1KMT2AGRM4DPP7 | |
| Lysine SCHEMBL8025646 | 0.89 | GRM4 (0.41) | TSHREPHX1KMT2AGRM4DPP7 | |
| Cyclohexylamine SCHEMBL7798074 | 0.89 | TSHR (0.46) | TSHREPHX1KMT2ADPP7DPP4 | |
| Cyclohexylamine SCHEMBL8035887 | 0.88 | GRIK1 (0.45) | EPHX1KMT2ADPP7DPP4FAP | |
| Cyclohexylamine SCHEMBL8035890 | 0.88 | GRIK1 (0.45) | EPHX1KMT2ADPP7DPP4FAP | |
| Cyclohexylamine SCHEMBL7798568 | 0.86 | MCOLN3 (0.45) | TSHREPHX1KMT2AMCOLN3GRIN2D | |
| Benzaldehyde SCHEMBL8035694 | 0.85 | KIF11 (0.42) | KMT2ATRPM8GRIK1GRIK2 | |
| 3-Hydroxybenzaldehyde SCHEMBL8039117 | 0.84 | KYNU (0.40) | KMT2A | |
| 3-Hydroxybenzaldehyde SCHEMBL8039109 | 0.84 | KYNU (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |