Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.48 |
| ▸ | RXRB | P28702 | 3/20 | 0.48 |
| ▸ | RXRG | P48443 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyramine SCHEMBL7799952 | 0.94 | TAAR1 (0.41) | RXRARXRBRXRGMAOBSRD5A2 | |
| Phenethylamine SCHEMBL7799179 | 0.94 | RXRA (0.52) | RXRARXRBRXRGMAOBTRIM24 | |
| SCHEMBL7802656 | 0.91 | RXRA (0.47) | RXRARXRBRXRGMAOBTRIM24 | |
| SCHEMBL7798437 | 0.89 | SRD5A2 (0.47) | RXRARXRBRXRGMAOBTRIM24 | |
| Tyramine SCHEMBL8039128 | 0.88 | SRD5A2 (0.41) | RXRARXRBRXRGMAOBSRD5A2 | |
| 4-Methylbenzoic Acid SCHEMBL7798106 | 0.88 | SRD5A2 (0.41) | RXRARXRBRXRGSRD5A2P4HB | |
| SCHEMBL8035858 | 0.88 | MAOB (0.46) | RXRARXRBRXRGMAOBTRIM24 | |
| Phenethylamine SCHEMBL7800387 | 0.87 | TAAR1 (0.44) | RXRARXRBRXRGMAOBSRD5A2 | |
| SCHEMBL7802496 | 0.86 | RXRA (0.46) | RXRARXRBRXRGMAOBTRIM24 | |
| Tyramine SCHEMBL8035697 | 0.85 | TAAR1 (0.51) | MAOBP4HBTAAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |