Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | XPO1 | O14980 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL7799012 | 0.91 | RXRA (0.42) | SRD5A2RXRARXRBRXRGTAAR1 | |
| SCHEMBL7798427 | 0.91 | SRD5A2 (0.40) | SRD5A2RXRARXRBRXRGTAAR1 | |
| Tyramine SCHEMBL7799952 | 0.90 | TAAR1 (0.41) | SRD5A2RXRARXRBRXRGTAAR1 | |
| 4-Methylbenzoic Acid SCHEMBL7798106 | 0.89 | SRD5A2 (0.41) | SRD5A2RXRARXRBRXRGTAAR1 | |
| Tyramine SCHEMBL8035895 | 0.88 | RXRA (0.48) | SRD5A2RXRARXRBRXRGTAAR1 | |
| SCHEMBL7798600 | 0.87 | SRD5A2 (0.46) | SRD5A2RXRARXRBKMT2ANR4A2 | |
| Tyramine SCHEMBL8035697 | 0.86 | TAAR1 (0.51) | TAAR1ALDH1A1KDM4EHTR1AADRA2A | |
| SCHEMBL8037475 | 0.86 | RXRA (0.44) | RXRARXRBRXRGNR4A2MAOB | |
| SCHEMBL7792606 | 0.84 | KDM4E (0.45) | RXRARXRBRXRGTAAR1ALDH1A1 | |
| Phenethylamine SCHEMBL7800387 | 0.83 | TAAR1 (0.44) | SRD5A2RXRARXRBRXRGTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |