SCHEMBL8035965

SCHEMBL8035965

CCOC(=O)[C@H](C)N(CCCCS)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.42
PIN1 Q13526 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NPC1 O15118 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MMP8 P22894 2/20 0.38
JAK2 O60674 1/20 0.38
RAB9A P51151 1/20 0.38
PAX8 Q06710 1/20 0.38
MAPT P10636 1/20 0.38
TP53 P04637 2/20 0.37
LMNA P02545 3/20 0.36
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
POLB P06746 2/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8031616 0.87 ALDH1A1 (0.38) SMN1; SMN2TDP1KMT2AMAPTLMNA
SCHEMBL8035968 0.86 PPARG (0.41) SMN1; SMN2TDP1NPC1MEN1KMT2A
SCHEMBL8030077 0.84 LMNA (0.38) SMN1; SMN2MAPTLMNAALDH1A1L3MBTL1
SCHEMBL8020317 0.83 FOLH1 (0.39) SMN1; SMN2NPC1MEN1KMT2AJAK2
SCHEMBL27577105 0.79 MEN1 (0.46) SMN1; SMN2PIN1TDP1NPC1MEN1
SCHEMBL10879663 0.75 NPC1 (0.41) SMN1; SMN2NPC1JAK2RAB9APAX8
SCHEMBL10525181 0.75 PIN1 (0.49) SMN1; SMN2PIN1TDP1NPC1MEN1
SCHEMBL6555981 0.74 CNR2 (0.40) SMN1; SMN2TDP1KMT2AMAPTLMNA
SCHEMBL6555980 0.74 CNR2 (0.40) SMN1; SMN2TDP1KMT2AMAPTLMNA
SCHEMBL11031009 0.74 NPC1 (0.50) NPC1JAK2RAB9APAX8TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786690-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2000-03-22 EP disclosed
US-5747235-A SILVER HALIDE ADSORBERS IN EMULSIONS FOR PHOTOGRAPHIC FILMS EASTMAN KODAK COMPANY (US) 1998-05-05 US disclosed
EP-0786690-A2 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1997-07-30 EP disclosed