SCHEMBL8035968

SCHEMBL8035968

CCOC(=O)[C@H](C)N(CCCCS)c1ccc(OC)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.41
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
HDAC3 O15379 3/20 0.39
HDAC4 P56524 3/20 0.39
HDAC1 Q13547 3/20 0.39
HDAC7 Q8WUI4 3/20 0.39
HDAC2 Q92769 3/20 0.39
HDAC10 Q969S8 3/20 0.39
HDAC11 Q96DB2 3/20 0.39
HDAC8 Q9BY41 3/20 0.39
HDAC6 Q9UBN7 3/20 0.39
HDAC9 Q9UKV0 3/20 0.39
HDAC5 Q9UQL6 3/20 0.39
BRD4 O60885 1/20 0.37
GAA P10253 2/20 0.36
KMT2A Q03164 2/20 0.36
GLA P06280 1/20 0.36
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8031616 0.86 ALDH1A1 (0.38) GAAKMT2AALDH1A1TSHRMAPK1
SCHEMBL8035965 0.86 SMN1; SMN2 (0.42) MMP8KMT2AALDH1A1TDP1L3MBTL1
SCHEMBL8030077 0.81 LMNA (0.38) ALDH1A1TSHRL3MBTL1SMN1; SMN2MAPT
SCHEMBL8031623 0.80 HDAC3 (0.40) PPARGHDAC3HDAC4HDAC1HDAC7
SCHEMBL8031618 0.80 HDAC3 (0.40) PPARGHDAC3HDAC4HDAC1HDAC7
SCHEMBL8031629 0.76 PPARG (0.64) PPARGMMP8MMP13HDAC3HDAC4
SCHEMBL8029785 0.76 LDHA (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL6555980 0.74 CNR2 (0.40) PPARGGAAKMT2AALDH1A1TSHR
SCHEMBL6555981 0.74 CNR2 (0.40) PPARGGAAKMT2AALDH1A1TSHR
SCHEMBL6555714 0.72 ALDH1A1 (0.37) GAAKMT2AALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786690-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2000-03-22 EP disclosed
US-5747235-A SILVER HALIDE ADSORBERS IN EMULSIONS FOR PHOTOGRAPHIC FILMS EASTMAN KODAK COMPANY (US) 1998-05-05 US disclosed
EP-0786690-A2 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1997-07-30 EP disclosed