Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504901 | 0.92 | MAPK10 (0.45) | GAACRHBPCRHR2HSD17B10POLB | |
| SCHEMBL2004924 | 0.92 | GAA (0.43) | GAACRHBPCRHR2HSD17B10POLB | |
| SCHEMBL10292556 | 0.89 | ALDH1A1 (0.45) | GAACRHBPCRHR2HSD17B10POLB | |
| SCHEMBL133847 | 0.89 | ALDH1A1 (0.48) | GAAHSD17B10POLBNPSR1ALDH1A1 | |
| SCHEMBL8165716 | 0.87 | ALDH1A1 (0.60) | GAAALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL10780259 | 0.87 | LMNA (0.47) | GAAHSD17B10POLBNPSR1ALDH1A1 | |
| SCHEMBL3573866 | 0.87 | CES2 (0.42) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL26108874 | 0.87 | CYP3A4 (0.48) | GAACRHBPCRHR2HSD17B10POLB | |
| SCHEMBL7822792 | 0.87 | GAA (0.40) | GAACRHBPCRHR2HSD17B10POLB | |
| SCHEMBL130476 | 0.86 | CRHBP (0.56) | GAACRHBPCRHR2HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61200173-A | — | — | None | — | — | JP | disclosed |
| WO-2022087148-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS | POSEIDA THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| US-20160266292-A1 | Coatable Polymer Polarizer | LIGHT POLYMERS HOLDING (KY) | 2016-09-15 | — | — | US | disclosed |
| US-20120070677-A1 | Flexible Metal-Clad Laminate and Manufacturing Method Thereof | SK INNOVATION CO., LTD. (KR) | 2012-03-22 | — | — | US | disclosed |
| JP-S61200173-A | PRODUCTION OF DISAZO PIGMENT | DAINIPPON INK & CHEM INC | 1986-09-04 | — | — | JP | disclosed |
| US-4144225-A | Novel aromatic diamine compounds and flame-resistant polyamide compositions containing said compounds | KANEBO, LTD. (JP) | 1979-03-13 | — | — | US | disclosed |