SCHEMBL8036634

SCHEMBL8036634

C/C=C/[C@H]1CO[C@H]([C@H]2CC[C@H]([C@H]3CC[C@H](c4ccc(F)cc4)CC3)CC2)OC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAP1LC3B Q9GZQ8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480891 0.99 MAP1LC3B (0.31) MAP1LC3B
SCHEMBL9163747 0.99 MAP1LC3B (0.31) MAP1LC3B
SCHEMBL9163744 0.99 MAP1LC3B (0.31) MAP1LC3B
SCHEMBL9480905 0.99 MAP1LC3B (0.31) MAP1LC3B
SCHEMBL9163763 0.99 MAP1LC3B (0.31) MAP1LC3B
SCHEMBL9163752 0.99 MAP1LC3B (0.31) MAP1LC3B
SCHEMBL9163757 0.99 MAP1LC3B (0.31) MAP1LC3B
SCHEMBL8038550 0.86 DRD2 (0.38) MAP1LC3B
SCHEMBL8040816 0.86 USP5 (0.32)
SCHEMBL8972185 0.85 DRD2 (0.39) MAP1LC3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0497176-B1 Four rings compounds and liquid crystal mixtures containing them MERCK PATENT GMBH (DE) 2000-04-05 EP disclosed
US-5478497-A For electro-optical purposes HOFFMANN-LA ROCHE INC. (US) 1995-12-26 US disclosed
EP-0497176-A2 Four rings compounds and liquid crystal mixtures containing them F. HOFFMANN-LA ROCHE AG (CH) 1992-08-05 EP disclosed