Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.51 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803678 | 0.92 | CHRNB2 (0.54) | CHRNB2CHRNA4KDM4ECACNA1ITRPV6 | |
| SCHEMBL14393395 | 0.86 | CHRNB2 (0.60) | CHRNB2CHRNA4KDM4ECACNA1ITRPV6 | |
| SCHEMBL8430036 | 0.85 | CHRNB2 (0.64) | CHRNB2CHRNA4KDM4ECACNA1ITRPV6 | |
| SCHEMBL17471175 | 0.84 | CHRNB2 (0.62) | CHRNB2CHRNA4KDM4ETRPV6KMT2A | |
| SCHEMBL803673 | 0.84 | CHRNB2 (0.58) | CHRNB2CHRNA4KDM4ETRPV6KMT2A | |
| SCHEMBL13597001 | 0.83 | KMT2A (0.60) | CHRNB2CHRNA4KDM4ECACNA1ITRPV6 | |
| SCHEMBL12120543 | 0.83 | CHRNB2 (0.60) | CHRNB2CHRNA4KDM4ECACNA1ITRPV6 | |
| SCHEMBL23028620 | 0.82 | CHRNB2 (0.64) | CHRNB2CHRNA4KDM4ECACNA1ITRPV6 | |
| SCHEMBL29508484 | 0.82 | CHRNB2 (0.64) | CHRNB2CHRNA4KDM4ECACNA1ITRPV6 | |
| SCHEMBL803087 | 0.82 | ACHE (0.49) | KDM4ETRPV6KMT2ASIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | CHRNB2 636/4885CHRNA4 720/4885KDM4E 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.