Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803095 | 0.91 | HSD11B1 (0.47) | ACHECCR3SIGMAR1HIF1AEPAS1 | |
| SCHEMBL803462 | 0.83 | CCR3 (0.67) | ACHECCR3SIGMAR1ALDH1A1 | |
| SCHEMBL19160313 | 0.83 | KDM4E (0.49) | ACHECCR3SIGMAR1TRPV6KDM4E | |
| SCHEMBL20314493 | 0.82 | HRH3 (0.49) | ACHECCR3ALDH1A1 | |
| SCHEMBL14768798 | 0.82 | CXCR4 (0.47) | ACHECCR3SIGMAR1HIF1AEPAS1 | |
| SCHEMBL803401 | 0.82 | MAPT (0.49) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL803669 | 0.82 | CHRNB2 (0.60) | ACHESIGMAR1TRPV6KDM4EALDH1A1 | |
| SCHEMBL4700460 | 0.81 | ACHE (0.49) | ACHECCR3SIGMAR1HIF1AEPAS1 | |
| SCHEMBL4700463 | 0.81 | ACHE (0.49) | ACHECCR3SIGMAR1HIF1AEPAS1 | |
| SCHEMBL17030671 | 0.81 | MEN1 (0.56) | ACHESIGMAR1HIF1AEPAS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | ACHE 746/4885CCR3 517/4885SIGMAR1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.