Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032828 | 0.88 | NPC1 (0.45) | MEN1KMT2AALDH1A1SGMS2NPC1 | |
| SCHEMBL8034163 | 0.87 | CTSV (0.47) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8039269 | 0.86 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1SGMS2NPC1 | |
| SCHEMBL8035938 | 0.85 | SRD5A1 (0.47) | MEN1KMT2ANPC1RAB9ACTSV | |
| SCHEMBL8039264 | 0.85 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1SGMS2NPC1 | |
| SCHEMBL8038345 | 0.84 | HPGD (0.52) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8022338 | 0.83 | TRPM8 (0.46) | MEN1KMT2ANPC1PKMRAB9A | |
| SCHEMBL8032086 | 0.83 | NPC1 (0.47) | MEN1KMT2ANPC1RAB9ACTSV | |
| SCHEMBL8037213 | 0.82 | MEN1 (0.51) | MEN1KMT2AALDH1A1SGMS2NPC1 | |
| SCHEMBL8039231 | 0.82 | CTSV (0.43) | MEN1KMT2AALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |