Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037440 | 0.97 | PDE10A (0.42) | PDE10AFAAH | |
| SCHEMBL8037444 | 0.96 | EPHX2 (0.43) | PDE10A | |
| SCHEMBL8041448 | 0.96 | EPHX2 (0.43) | PDE10A | |
| SCHEMBL8037415 | 0.93 | S1PR1 (0.41) | S1PR1APP | |
| SCHEMBL8037394 | 0.91 | POLB (0.46) | S1PR1APP | |
| SCHEMBL8035725 | 0.89 | KDM4E (0.43) | S1PR1 | |
| SCHEMBL8025554 | 0.87 | MTNR1A (0.42) | S1PR1APP | |
| SCHEMBL8035132 | 0.87 | S1PR1 (0.38) | S1PR1APP | |
| SCHEMBL8041325 | 0.86 | ALDH1A1 (0.45) | S1PR1 | |
| SCHEMBL8041411 | 0.83 | S1PR1 (0.43) | S1PR1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |