Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037394 | 0.91 | POLB (0.46) | ALDH1A1KDM4EPOLBS1PR1L3MBTL1 | |
| SCHEMBL8035725 | 0.87 | KDM4E (0.43) | ALDH1A1KDM4EPOLBHTTRAB9A | |
| SCHEMBL8037435 | 0.86 | PDE10A (0.41) | S1PR1 | |
| SCHEMBL8037440 | 0.85 | PDE10A (0.42) | — | |
| SCHEMBL8037444 | 0.84 | EPHX2 (0.43) | — | |
| SCHEMBL8041448 | 0.84 | EPHX2 (0.43) | — | |
| SCHEMBL8037415 | 0.84 | S1PR1 (0.41) | ALDH1A1POLBS1PR1KMT2AMEN1 | |
| SCHEMBL8041411 | 0.83 | S1PR1 (0.43) | ALDH1A1KDM4EPOLBHTTS1PR1 | |
| SCHEMBL8025554 | 0.83 | MTNR1A (0.42) | KDM4ES1PR1 | |
| SCHEMBL8041695 | 0.82 | MTNR1B (0.43) | ALDH1A1KDM4EPOLBHTTS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |