Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038941 | 0.96 | ALDH1A1 (0.47) | HRH3ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8040494 | 0.80 | ACHE (0.55) | HRH3ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8037120 | 0.79 | MEN1 (0.47) | ALDH1A1KMT2ALMNAMAPTCRHBP | |
| SCHEMBL8040498 | 0.78 | MEN1 (0.49) | ALDH1A1KMT2ALMNAMAPTCRHBP | |
| SCHEMBL8040471 | 0.78 | MEN1 (0.49) | ALDH1A1KMT2ALMNAMAPTCRHBP | |
| SCHEMBL8027126 | 0.75 | RAB9A (0.45) | HRH3ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8038946 | 0.74 | MAPT (0.46) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7567294 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL8043322 | 0.72 | MEN1 (0.38) | ALDH1A1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL7466959 | 0.71 | TSHR (0.49) | ALDH1A1KMT2ALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110911-A | ADMINISTERING NEUROPROTECTANT/ANTICONVULSANT TO PATIENT | WARNER-LAMBERT COMPANY (US) | 2000-08-29 | — | — | US | disclosed |