Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483587 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL28452792 | 0.79 | ALDH1A1 (0.35) | ALDH1A1CYP2C19 | |
| SCHEMBL10955658 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53 | |
| SCHEMBL29176956 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRTP53CYP2D6CYP1A2 | |
| SCHEMBL31738516 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRTP53CYP2D6CYP1A2 | |
| SCHEMBL20343323 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL85493 | 0.73 | TSHR (0.57) | ALDH1A1TSHRTP53CYP2D6CYP2C19 | |
| SCHEMBL11570554 | 0.72 | TSHR (0.36) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL17449769 | 0.72 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL24721851 | 0.70 | PIK3CD (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846300-B2 | Developer for processing lithographic printing plate precursor, method for manufacturing lithographic printing plate by using the developer, and printing method | FUJIFILM CORPORATION (JP) | 2014-09-30 | — | — | US | disclosed |
| US-8785655-B2 | Ionic liquid solvents | DUBLIN CITY UNIVERSITY (IE) | 2014-07-22 | — | — | US | disclosed |
| US-20130157199-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2013-06-20 | — | — | US | disclosed |
| US-20130014658-A1 | DEVELOPER FOR PROCESSING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING LITHOGRAPHIC PRINTING PLATE BY USING THE DEVELOPER, AND PRINTING METHOD | FUJIFILM CORPORATION (JP) | 2013-01-17 | — | — | US | disclosed |
| US-20120071661-A1 | Ionic Liquid Solvents | DUBLIN CITY UNIVERSITY (IE) | 2012-03-22 | — | — | US | disclosed |
| US-20070015771-A1 | Lonidamine analogs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071661-A1 | Ionic Liquid Solvents | EBP, PAICS, HACD3 | ALDH1A1 834/4885TSHR 4680/4885TP53 1787/4885 |
| US-20070015771-A1 | Lonidamine analogs | LONP1, LPXN, QDPR | ALDH1A1 184/4885TSHR 3215/4885TP53 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.