Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027781 | 0.90 | ABCC1 (0.40) | MMP13MAOAMAOBMMP2MMP9 | |
| SCHEMBL8038293 | 0.87 | TSPO (0.39) | ACACBALDH1A1ACACAKDM4E | |
| SCHEMBL8037926 | 0.87 | TSPO (0.39) | ACACBALDH1A1ACACAKDM4E | |
| SCHEMBL6406664 | 0.87 | TSPO (0.39) | ACACBALDH1A1ACACAKDM4E | |
| SCHEMBL8037891 | 0.85 | TSPO (0.40) | ACACBALDH1A1ACACAKDM4E | |
| SCHEMBL8041283 | 0.79 | MAOB (0.39) | MAOBMMP2MMP9ALDH1A1 | |
| SCHEMBL8038304 | 0.78 | PTPN1 (0.40) | MAOBABCC1ALDH1A1 | |
| SCHEMBL8039546 | 0.78 | PTPN1 (0.40) | MAOBABCC1ALDH1A1 | |
| SCHEMBL8039708 | 0.78 | PTPN1 (0.40) | MAOBABCC1ALDH1A1 | |
| SCHEMBL6405116 | 0.78 | PTPN1 (0.40) | MAOBABCC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |