Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027781 | 0.89 | ABCC1 (0.40) | MAOBMCL1BCL2L1APPEPHX2 | |
| SCHEMBL8038304 | 0.85 | PTPN1 (0.40) | MAOBEPHX2STAT3LMNAALDH1A1 | |
| SCHEMBL6405116 | 0.85 | PTPN1 (0.40) | MAOBEPHX2STAT3LMNAALDH1A1 | |
| SCHEMBL8039708 | 0.85 | PTPN1 (0.40) | MAOBEPHX2STAT3LMNAALDH1A1 | |
| SCHEMBL8039546 | 0.85 | PTPN1 (0.40) | MAOBEPHX2STAT3LMNAALDH1A1 | |
| SCHEMBL8039689 | 0.84 | PTPN1 (0.38) | MAOBMCL1EPHX2STAT3LMNA | |
| SCHEMBL8037976 | 0.79 | MMP13 (0.36) | MAOBMMP2MMP9ALDH1A1 | |
| SCHEMBL8038293 | 0.77 | TSPO (0.39) | LMNANPSR1ALDH1A1TSHR | |
| SCHEMBL8037926 | 0.77 | TSPO (0.39) | LMNANPSR1ALDH1A1TSHR | |
| SCHEMBL6406664 | 0.77 | TSPO (0.39) | LMNANPSR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |