Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422791 | 0.86 | MAPT (0.57) | KDM4EMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL28545286 | 0.84 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL8037607 | 0.83 | ALDH1A1 (0.60) | MAPTALDH1A1HDAC8ATMHTT | |
| SCHEMBL15687652 | 0.82 | CA1 (0.61) | KDM4EMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL8033266 | 0.81 | MAPT (0.67) | MAPTALDH1A1PTGER4HTTMEN1 | |
| SCHEMBL4539438 | 0.80 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL4538645 | 0.80 | MAPT (0.54) | KDM4EMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL23630654 | 0.79 | CASR (0.49) | KDM4EMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL30181799 | 0.79 | CASR (0.49) | KDM4EMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL8037982 | 0.79 | KDM4E (0.54) | KDM4EMAPTALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |