Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | PPM1D | O15297 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | CD38 | P28907 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237125 | 0.90 | MRGPRX4 (0.57) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL4538645 | 0.86 | MAPT (0.54) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL15687652 | 0.86 | CA1 (0.61) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL31072837 | 0.85 | HDAC8 (0.57) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL4539438 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL4308882 | 0.84 | ABL1 (0.51) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL29343403 | 0.83 | MAPT (0.49) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL8033328 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTMRGPRX4PPM1DLOXL2 | |
| SCHEMBL8024498 | 0.81 | MAPT (0.53) | ALDH1A1MAPTPTGER4LMNAL3MBTL1 | |
| SCHEMBL1180032 | 0.81 | LOXL2 (0.53) | KDM4EALDH1A1MAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |