Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538645 | 0.87 | MAPT (0.54) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL8037982 | 0.84 | KDM4E (0.54) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL5363438 | 0.83 | CA1 (0.51) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL4535606 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTTSHRMAPK1LMNA | |
| SCHEMBL12004538 | 0.82 | GAA (0.54) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL14977866 | 0.82 | GAA (0.54) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL4308882 | 0.82 | ABL1 (0.51) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL15687652 | 0.82 | CA1 (0.61) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL8033332 | 0.81 | MEN1 (0.54) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL4542148 | 0.81 | LMNA (0.53) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |