Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | VSIG8 | P0DPA2 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050044 | 0.87 | GABRA1 (0.43) | KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8050551 | 0.85 | KIF11 (0.43) | — | |
| SCHEMBL4335836 | 0.85 | ALOX15 (0.58) | ALOX15 | |
| SCHEMBL4338529 | 0.83 | GPR17 (0.48) | KDM4EHPGDCYP2C9 | |
| SCHEMBL4351594 | 0.80 | TUBB4A (0.58) | KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL4342254 | 0.76 | GAA (0.60) | ALOX15KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL8050911 | 0.75 | ALOX15 (0.51) | ALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL4337024 | 0.74 | BUB1 (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL4348744 | 0.73 | MAP2 (0.50) | KDM4EALDH1A1HPGDVSIG8 | |
| SCHEMBL4340498 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |