Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041445 | 0.78 | EPHX2 (0.41) | — | |
| SCHEMBL8041408 | 0.78 | SMN1; SMN2 (0.32) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL8025495 | 0.77 | KMT2A (0.48) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL8037861 | 0.76 | PPIA (0.41) | PPIAMAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL8040243 | 0.74 | PPIA (0.47) | PPIAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8025492 | 0.74 | PPIA (0.49) | PPIAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8037250 | 0.72 | TAS1R3 (0.45) | PPIAMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL8035160 | 0.71 | KMT2A (0.39) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8037862 | 0.71 | CYP3A4 (0.38) | MAPTALDH1A1CYP3A4HTTNPSR1 | |
| SCHEMBL8035106 | 0.70 | COMT (0.36) | KMT2AMEN1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |