Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 9/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9425165 | 0.99 | SLC6A2 (0.37) | SLC6A2CRHR1ROCK1MAPTMAPK1 | |
| SCHEMBL8056707 | 0.93 | SLC6A2 (0.41) | SLC6A2CRHR1ROCK1MAPTGCGR | |
| Hydrochloric Acid SCHEMBL8038855 | 0.92 | SLC6A2 (0.40) | SLC6A2CRHR1ROCK1MAPTGCGR | |
| SCHEMBL8050470 | 0.88 | ROCK1 (0.37) | SLC6A2ROCK1MAPTMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL8051640 | 0.86 | ROCK1 (0.36) | SLC6A2ROCK1MAPTMAPK1KDM4E | |
| SCHEMBL8050077 | 0.86 | MAPT (0.33) | SLC6A2MAPTMAPK1NPSR1GCGR | |
| SCHEMBL8054079 | 0.85 | CRHR1 (0.37) | SLC6A2CRHR1ROCK1GCGRHTT | |
| Hydrochloric Acid SCHEMBL8056275 | 0.85 | MAPT (0.33) | SLC6A2MAPTMAPK1NPSR1GCGR | |
| Hydrochloric Acid SCHEMBL8052106 | 0.84 | CRHR1 (0.36) | SLC6A2CRHR1ROCK1GCGRHTT | |
| SCHEMBL9425844 | 0.83 | NR1H2 (0.37) | SLC6A2MAPTMAPK1NPSR1LATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |