Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 9/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8052106 | 0.99 | CRHR1 (0.36) | CRHR1ROCK1SLC6A2MEN1KMT2A | |
| SCHEMBL8056707 | 0.87 | SLC6A2 (0.41) | CRHR1ROCK1SLC6A2CYP2A6GCGR | |
| Hydrochloric Acid SCHEMBL8038855 | 0.86 | SLC6A2 (0.40) | CRHR1ROCK1SLC6A2CYP2A6GCGR | |
| SCHEMBL8039432 | 0.85 | SLC6A2 (0.37) | CRHR1ROCK1SLC6A2CYP2A6GCGR | |
| SCHEMBL8050470 | 0.84 | ROCK1 (0.37) | ROCK1SLC6A2MEN1KMT2ACYP2A6 | |
| Hydrochloric Acid SCHEMBL9425165 | 0.84 | SLC6A2 (0.37) | CRHR1ROCK1SLC6A2CYP2A6GCGR | |
| Hydrochloric Acid SCHEMBL8051640 | 0.83 | ROCK1 (0.36) | ROCK1SLC6A2MEN1KMT2ACYP2A6 | |
| SCHEMBL8053422 | 0.81 | ROCK1 (0.35) | ROCK1SLC6A2CYP2A6 | |
| SCHEMBL8050534 | 0.81 | ROCK1 (0.35) | CRHR1ROCK1SLC6A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL8056254 | 0.80 | ROCK1 (0.34) | CRHR1ROCK1SLC6A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |