Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875288 | 0.76 | ALDH1A1 (0.60) | KDM4ECYP3A4MEN1CYP2D6CASP1 | |
| Hydrochloric Acid SCHEMBL10662272 | 0.75 | ALDH1A1 (0.58) | KDM4ECYP3A4MEN1CYP2D6CASP1 | |
| SCHEMBL29664763 | 0.73 | MAOA (0.60) | KDM4ECYP3A4MEN1CYP2D6CASP1 | |
| SCHEMBL1010356 | 0.73 | MAOA (0.60) | KDM4ECYP3A4MEN1CYP2D6CASP1 | |
| SCHEMBL3877767 | 0.71 | KDM4E (1.00) | KDM4ECYP3A4MEN1CYP2D6CASP1 | |
| SCHEMBL1007423 | 0.69 | KDM4E (0.54) | KDM4EHTR2CALDH1A1HPGDGAA | |
| SCHEMBL11831581 | 0.69 | CA1 (0.46) | KDM4ECYP3A4MEN1CYP2D6CASP1 | |
| SCHEMBL19382614 | 0.69 | CYP1A2 (0.61) | KDM4EMEN1KMT2AHTR2ACYP1A2 | |
| Harmaline SCHEMBL29626541 | 0.69 | KDM4E (1.00) | KDM4ECYP3A4MEN1CYP2D6CASP1 | |
| Harmaline SCHEMBL199260 | 0.69 | KDM4E (1.00) | KDM4ECYP3A4MEN1CYP2D6CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048868-A | CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS; ANTIDEPRESSANTS | CEMAF (FR) | 2000-04-11 | — | — | US | disclosed |