Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 17/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5213937 | 0.95 | F2 (0.34) | F2PRSS1PRSS2PRSS3OPRM1 | |
| Trifluoroacetic Acid SCHEMBL5214259 | 0.90 | MAOA (0.35) | F2PRSS1PRSS2PRSS3OPRM1 | |
| SCHEMBL7434072 | 0.89 | F2 (0.37) | F2OPRM1OPRD1OPRK1ADRA2C | |
| Trifluoroacetic Acid SCHEMBL7426179 | 0.87 | F2 (0.36) | F2PRSS1PRSS2PRSS3OPRM1 | |
| Trifluoroacetic Acid SCHEMBL6486974 | 0.84 | ACHE (0.38) | OPRM1OPRD1OPRK1ADRA2C | |
| Trifluoroacetic Acid SCHEMBL5214692 | 0.83 | MAOA (0.35) | F2PRSS1PRSS2PRSS3OPRM1 | |
| Trifluoroacetic Acid SCHEMBL7423644 | 0.83 | ACHE (0.39) | F2PRSS1PRSS2PRSS3OPRM1 | |
| Trifluoroacetic Acid SCHEMBL5210467 | 0.82 | F2 (0.37) | F2PRSS1PRSS2PRSS3OPRM1 | |
| Trifluoroacetic Acid SCHEMBL4809174 | 0.80 | RXRA (0.37) | OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL7428960 | 0.79 | MAPK14 (0.36) | F2PRSS1PRSS2PRSS3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000077027-A2 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2000-12-21 | — | — | WO | disclosed |