Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250659 | 0.89 | NCOA1 (0.46) | LMNAMAPK1L3MBTL1TDP1NCOA1 | |
| SCHEMBL8040741 | 0.87 | SYK (0.50) | LMNAMAPK1L3MBTL1TDP1HTT | |
| SCHEMBL8040823 | 0.85 | SYK (0.49) | LMNAMAPK1L3MBTL1TDP1HTT | |
| SCHEMBL674709 | 0.85 | MAPK1 (0.47) | LMNAMAPK1L3MBTL1TDP1NCOA1 | |
| SCHEMBL1096473 | 0.80 | NCOA1 (0.68) | LMNAMAPK1L3MBTL1TDP1NCOA1 | |
| SCHEMBL8487523 | 0.80 | NCOA1 (0.42) | LMNAMAPK1TDP1NCOA1NCOA3 | |
| SCHEMBL17528779 | 0.79 | LTA4H (0.36) | LMNANCOA1NCOA3ALDH1A1RAB9A | |
| SCHEMBL444404 | 0.79 | HTT (0.48) | LMNATDP1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL446426 | 0.79 | HTT (0.48) | LMNATDP1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL27704654 | 0.79 | HTT (0.48) | LMNATDP1HTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364899-A | Polycarbonate, zinc carboxylate, glass fibers, polytetrafluoroethylene, polydimethysiloxane, triphenyl phosphate | DENKI KAGAKU KOGUO KABUSHIKI KAISHA (JP) | 1994-11-15 | — | — | US | disclosed |