Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8035555 | 1.00 | DPEP1 (0.47) | DPEP1NPC1RAB9ATDP1IDO1 | |
| Cyclohexylamine SCHEMBL7798128 | 0.89 | DPEP1 (0.45) | DPEP1NPC1RAB9ATDP1IDO1 | |
| Cyclohexylamine SCHEMBL8037697 | 0.85 | GRIK1 (0.41) | DPEP1NPC1RAB9AGRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8037514 | 0.85 | GRIK1 (0.42) | DPEP1NPC1RAB9AGRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8037696 | 0.85 | GRIK1 (0.41) | DPEP1NPC1RAB9AGRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8037511 | 0.85 | GRIK1 (0.42) | DPEP1NPC1RAB9AGRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8041252 | 0.82 | TP53 (0.41) | NPC1RAB9AMAOAMAOBKIF11 | |
| Cyclohexylamine SCHEMBL8039367 | 0.82 | ALDH1A1 (0.47) | TDP1ALDH1A1MAOAMAOBKIF11 | |
| Cyclohexylamine SCHEMBL8041254 | 0.82 | TP53 (0.41) | NPC1RAB9AMAOAMAOBKIF11 | |
| Cyclohexylamine SCHEMBL8039363 | 0.82 | ALDH1A1 (0.47) | TDP1ALDH1A1MAOAMAOBKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |