Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 2/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 7/20 | 0.35 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.30 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446319 | 0.84 | SOAT1 (0.49) | ACAT1SOAT1SOAT2KDM4ETP53 | |
| SCHEMBL9446276 | 0.84 | SOAT1 (0.49) | ACAT1SOAT1SOAT2KDM4ETP53 | |
| SCHEMBL9446314 | 0.84 | SOAT1 (0.49) | ACAT1SOAT1SOAT2KDM4ETP53 | |
| SCHEMBL9446344 | 0.84 | SOAT1 (0.49) | ACAT1SOAT1SOAT2KDM4ETP53 | |
| SCHEMBL9446308 | 0.84 | SOAT1 (0.49) | ACAT1SOAT1SOAT2KDM4ETP53 | |
| SCHEMBL893576 | 0.78 | SOAT1 (0.47) | ACAT1SOAT1SOAT2KDM4EMAPT | |
| SCHEMBL8072066 | 0.77 | ACAT1 (0.43) | ACAT1SOAT1SOAT2KDM4ETP53 | |
| SCHEMBL8041447 | 0.76 | SOAT2 (0.47) | ACAT1SOAT1SOAT2MAPTESR1 | |
| SCHEMBL8049433 | 0.75 | SOAT2 (0.46) | ACAT1SOAT1SOAT2MAPTESR1 | |
| SCHEMBL8042243 | 0.75 | SOAT2 (0.46) | ACAT1SOAT1SOAT2MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874812-B1 | NOVEL 2,3,5-TRIMETHYL-4-HYDROXY ANILIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | PF MEDICAMENT (FR) | 2000-04-05 | — | — | EP | disclosed |