Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 2/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446276 | 0.86 | SOAT1 (0.49) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL9446344 | 0.86 | SOAT1 (0.49) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL9446319 | 0.86 | SOAT1 (0.49) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL9446314 | 0.86 | SOAT1 (0.49) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL9446308 | 0.86 | SOAT1 (0.49) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL8080878 | 0.84 | SOAT2 (0.48) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL8080772 | 0.78 | SOAT2 (0.50) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL8041409 | 0.77 | ACAT1 (0.44) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL9446297 | 0.76 | SOAT1 (0.53) | ACAT1SOAT1SOAT2MAPTKDM4E | |
| SCHEMBL9446388 | 0.76 | SOAT1 (0.53) | ACAT1SOAT1SOAT2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871611-B1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PF MEDICAMENT (FR) | 2000-09-13 | — | — | EP | claimed |
| US-5760087-A | ANTICHOLESTEROL AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1998-06-02 | — | — | US | claimed |
| EP-0871611-B1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PF MEDICAMENT (FR) | 2000-09-13 | — | — | EP | disclosed |
| US-5760087-A | ANTICHOLESTEROL AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1998-06-02 | — | — | US | disclosed |