Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.49 |
| ▸ | ACAT1 | P24752 | 2/20 | 0.49 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446314 | 1.00 | SOAT1 (0.49) | SOAT1ACAT1SOAT2KDM4ETP53 | |
| SCHEMBL9446344 | 1.00 | SOAT1 (0.49) | SOAT1ACAT1SOAT2KDM4ETP53 | |
| SCHEMBL9446319 | 1.00 | SOAT1 (0.49) | SOAT1ACAT1SOAT2KDM4ETP53 | |
| SCHEMBL9446276 | 1.00 | SOAT1 (0.49) | SOAT1ACAT1SOAT2KDM4ETP53 | |
| SCHEMBL8072066 | 0.86 | ACAT1 (0.43) | SOAT1ACAT1SOAT2KDM4ETP53 | |
| SCHEMBL8041409 | 0.84 | ACAT1 (0.44) | SOAT1ACAT1SOAT2KDM4ETP53 | |
| SCHEMBL8041413 | 0.81 | SOAT1 (0.54) | SOAT1ACAT1SOAT2KDM4ETP53 | |
| SCHEMBL8031803 | 0.79 | SOAT1 (0.45) | SOAT1ACAT1SOAT2KDM4EESR1 | |
| SCHEMBL9446337 | 0.78 | SOAT1 (0.53) | SOAT1ACAT1SOAT2KDM4EMAPT | |
| SCHEMBL9446388 | 0.78 | SOAT1 (0.53) | SOAT1ACAT1SOAT2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | claimed |
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |