Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.39 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL804144 | 0.87 | KDM4E (0.54) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| Hydrochloric Acid SCHEMBL3350621 | 0.72 | KDM4E (0.38) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL22662448 | 0.70 | KDM4E (0.52) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL960674 | 0.69 | KDM4E (0.40) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL10936278 | 0.69 | NOS2 (0.31) | CYP2C19NOS2 | |
| SCHEMBL6534968 | 0.67 | CYP2C19 (0.62) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL3465587 | 0.67 | LMNA (0.37) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL9842065 | 0.67 | LMNA (0.37) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL15340969 | 0.66 | ACLY (0.39) | KDM4ECYP2C19FFAR1CPT2TDP1 | |
| Sulfuric Acid SCHEMBL6263301 | 0.66 | TSHR (0.42) | KDM4ECYP2C19CYP2D6TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860874-B | Bicyclic or tricyclic steric hindrance alkoxyamine and preparation method thereof | 巴斯夫欧洲公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104860874-A | Bi-or tricyclic sterically hindered alkoxyamines and process for their preparation | BASF SE | 2015-08-26 | — | — | CN | disclosed |
| CN-102482217-B | Bicyclic or tricyclic sterically hindered alkoxyamines and process for their preparation | BASF SE | 2015-05-27 | — | — | CN | disclosed |