SCHEMBL8041554

SCHEMBL8041554

NCCc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.58
TAAR1 Q96RJ0 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
CYP2A6 P11509 1/20 0.58
LOXL2 Q9Y4K0 1/20 0.58
ALDH1A1 P00352 4/20 0.56
SRD5A2 P31213 3/20 0.54
HTR6 P50406 1/20 0.52
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
ATM Q13315 2/20 0.48
KDM4E B2RXH2 1/20 0.48
HTR1A P08908 1/20 0.48
ADRA2A P08913 1/20 0.48
SLC6A2 P23975 1/20 0.48
CYP2C19 P33261 1/20 0.48
HTR3A P46098 1/20 0.48
BACE1 P56817 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9467870 0.98 HTR2A (0.56) HTR2ATAAR1SMN1; SMN2CYP2A6LOXL2
Benzophenone SCHEMBL4653152 0.91 TAAR1 (0.64) HTR2ATAAR1SMN1; SMN2CYP2A6LOXL2
Benzophenone SCHEMBL4622258 0.91 TAAR1 (0.64) HTR2ATAAR1SMN1; SMN2CYP2A6LOXL2
SCHEMBL7889494 0.87 ALDH1A1 (0.67) SMN1; SMN2ALDH1A1SRD5A2KMT2AMEN1
SCHEMBL7898126 0.85 ALDH1A1 (0.64) ALDH1A1SRD5A2KMT2AMEN1L3MBTL1
SCHEMBL203283 0.83 ALDH1A1 (0.61) TAAR1SMN1; SMN2LOXL2ALDH1A1SRD5A2
Sulfanilamide SCHEMBL27496763 0.83 MEN1 (0.64) HTR6KMT2AMEN1
SCHEMBL10905589 0.83 ATM (0.59) HTR2ATAAR1SMN1; SMN2CYP2A6LOXL2
SCHEMBL9148047 0.82 MAOB (0.69) ALDH1A1SRD5A2KMT2AMEN1HDAC1
SCHEMBL9039075 0.82 TAAR1 (0.69) TAAR1SMN1; SMN2CYP2A6ALDH1A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119510643-A Method for improving quality control of dopamine hydrochloride injection 广州艾奇西医药科技有限公司 2025-02-25 CN claimed
CN-116731375-A Polymer surface modification method, obtained surface modified polymer and application thereof 中国科学院赣江创新研究院 2023-09-12 CN claimed
CN-119510643-B Method for improving quality control of dopamine hydrochloride injection 广州艾奇西医药科技有限公司 2025-07-25 CN disclosed
CN-119510643-A Method for improving quality control of dopamine hydrochloride injection 广州艾奇西医药科技有限公司 2025-02-25 CN disclosed
CN-119510643-A Method for improving quality control of dopamine hydrochloride injection 广州艾奇西医药科技有限公司 2025-02-25 CN disclosed
CN-116731375-A Polymer surface modification method, obtained surface modified polymer and application thereof 中国科学院赣江创新研究院 2023-09-12 CN disclosed
EP-3554571-A1 HYDROPHOBIC ACTIVE AGENT PARTICLE COATINGS AND METHODS FOR TREATMENT Surmodics, Inc. (US) 2019-10-23 EP disclosed
WO-2018112196-A1 HYDROPHOBIC ACTIVE AGENT PARTICLE COATINGS AND METHODS FOR TREATMENT SURMODICS, INC. (US) 2018-06-21 WO disclosed
US-9399633-B2 Photoinitiators COLOPLAST A/S (DK) 2016-07-26 US disclosed
US-20160060243-A1 NOVEL PHOTOINITIATORS COLOPLAST A/S (DK) 2016-03-03 US disclosed
US-9212160-B2 Photoinitiators COLOPLAST A/S (DK) 2015-12-15 US disclosed
US-20070104757-A1 LATENT REACTIVE BLOOD COMPATIBLE AGENTS Surmodics Coatings, LLC 2007-05-10 US disclosed
US-20070082022-A1 LATENT REACTIVE BLOOD COMPATIBLE AGENTS Surmodics Coatings, LLC 2007-04-12 US disclosed
EP-0755949-B1 Radiation curable masses containing covalently bonded photoinitiators BASF AG (DE) 2000-04-12 EP disclosed
US-5859084-A Radiation-curable compositions containing photoinitiators linked by a covalent bond BASF AKTIENGESELLSCHAFT (DE) 1999-01-12 US disclosed
EP-0755949-A1 Radiation curable masses containing covalently bonded photoinitiators BASF AKTIENGESELLSCHAFT (DE) 1997-01-29 EP disclosed
US-5232946-A Promoting weight gain and reduction of blood sugar and fat deposits in animals, feed efficiency DR. KARL THOMAE GMBH (DE) 1993-08-03 US disclosed
EP-0400011-A1 NEW PHENYLETHANOLAMINES. BOEHRINGER INGELHEIM VETMED (DE) 1990-12-05 EP disclosed
EP-0375791-A1 Phenyl ethanol amines, their use as pharmaceutical compounds and as performance stimulants in animals, as well as processes for their preparation BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1990-07-04 EP disclosed
WO-1990006299-A1 NEW PHENYLETHANOLAMINES BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1990-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160060243-A1 NOVEL PHOTOINITIATORS UROD, PUF60, PPOX HTR2A 961/4885TAAR1 689/4885SMN1; SMN2 4690/4885
US-20070082022-A1 LATENT REACTIVE BLOOD COMPATIBLE AGENTS FGB, HLA-A, HLA-C HTR2A 2644/4885TAAR1 1262/4885SMN1; SMN2 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.