Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898126 | 0.98 | ALDH1A1 (0.64) | ALDH1A1SRD5A2HDAC1ATML3MBTL1 | |
| SCHEMBL27628329 | 0.90 | SRD5A2 (0.59) | ALDH1A1SRD5A2HDAC1L3MBTL1MEN1 | |
| SCHEMBL8026026 | 0.89 | TDP1 (0.60) | ALDH1A1SRD5A2HDAC1ATML3MBTL1 | |
| SCHEMBL28251464 | 0.89 | HDAC1 (0.62) | ALDH1A1SRD5A2HDAC1TDP1MEN1 | |
| SCHEMBL8041554 | 0.87 | HTR2A (0.58) | ALDH1A1SRD5A2HDAC1ATML3MBTL1 | |
| SCHEMBL4605419 | 0.87 | L3MBTL1 (0.58) | ALDH1A1SRD5A2L3MBTL1KMT2ARAB9A | |
| Benzophenone SCHEMBL28417175 | 0.87 | L3MBTL1 (0.58) | ALDH1A1SRD5A2L3MBTL1KMT2ARAB9A | |
| SCHEMBL4138253 | 0.87 | SRD5A2 (0.75) | ALDH1A1SRD5A2HDAC1FFAR1SMN1; SMN2 | |
| SCHEMBL5433433 | 0.87 | TDP1 (0.58) | ALDH1A1SRD5A2HDAC1ATML3MBTL1 | |
| SCHEMBL5535431 | 0.87 | ALDH1A1 (0.56) | ALDH1A1SRD5A2HDAC1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746187-B2 | Compound, resin, polycarbonate resin, and optical molded article | MITSUI CHEMICALS, INC. (JP) | 2023-09-05 | — | — | US | disclosed |
| US-20230022186-A1 | COMPOUND, RESIN, POLYCARBONATE RESIN, AND OPTICAL MOLDED ARTICLE | MITSUI CHEMICALS, INC. (JP) | 2023-01-26 | — | — | US | disclosed |
| US-20220024951-A1 | Transition Metal Compound and Catalyst Composition Comprising Same | LG CHEM, LTD. (KR) | 2022-01-27 | — | — | US | disclosed |
| US-6190580-B1 | DIARYL-NAPHTHOPYRAN PHOTOCHROMIC SUBSTANCE OF GIVEN LINKAGE FORMULA WHICH HAVE A REDUCED TENDENCY TO MIGRATE IN PLASTICS; COMPOUNDS MADE BY ACYLATION FOLLOWED BY NUCLEOPHILIC ADDITION OF METAL ACETYLIDE AND CONDENSATION WITH A DIARYL ALCOHOL | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-02-20 | — | — | US | disclosed |
| US-6036890-A | STABLE PHOTOCHROMIC DYE; SUNGLASS LENSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5998496-A | ABSORBING RADIATION | SPECTRA GROUP LIMITED, INC. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0871607-A4 | PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS | SPECTRA GROUP LTD INC (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0770116-B1 | DIARYL-2H-NAPHTHOPYRANES | RODENSTOCK OPTIK G (DE) | 1999-09-22 | — | — | EP | disclosed |
| US-5952515-A | PHOTOCHROMIC SUBSTANCE HAS AN ARYL SUBSTITUENT WHICH REDUCES THE MIGRATION OF THE MOLECULES IN PLASTICS | OPTISCHE WERKE G. RODENSTOCK (DE) | 1999-09-14 | — | — | US | disclosed |
| EP-0686685-B1 | Photochromic dye | RODENSTOCK OPTIK G (DE) | 1998-12-02 | — | — | EP | disclosed |
| EP-0871607-A1 | PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS | SPECTRA GROUP LIMITED INC (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997016406-A1 | PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS | SPECTRA GROUP LIMITED, INC. (US) | 1997-05-09 | — | — | WO | disclosed |
| EP-0770116-A1 | DIARYL-2H-NAPHTHOPYRANES | Optische Werke G. Rodenstock (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001884-A1 | DIARYL-2H-NAPHTHOPYRANES | OPTISCHE WERKE G. RODENSTOCK (DE) | 1996-01-25 | — | — | WO | disclosed |
| EP-0686685-A2 | Photochromic dye | Optische Werke G. Rodenstock (DE) | 1995-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746187-B2 | Compound, resin, polycarbonate resin, and optical molded article | ARL1, RER1, SEM1 | ALDH1A1 1237/4885SRD5A2 253/4885HDAC1 1242/4885 |
| US-20230022186-A1 | COMPOUND, RESIN, POLYCARBONATE RESIN, AND OPTICAL MOLDED ARTICLE | ARL1, RER1, SEM1 | ALDH1A1 1237/4885SRD5A2 253/4885HDAC1 1242/4885 |
| US-20220024951-A1 | Transition Metal Compound and Catalyst Composition Comprising Same | TRMT1, MRM1, EMG1 | ALDH1A1 175/4885SRD5A2 1932/4885HDAC1 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.