Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
| ▸ | UNG | P13051 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8041254 | 1.00 | TP53 (0.41) | TP53ATMHTTSLC1A1MAOA | |
| Lysine SCHEMBL8039357 | 0.88 | CTSB (0.42) | TP53ATMHTTDPP8DPP9 | |
| Lysine SCHEMBL8039360 | 0.88 | CTSB (0.42) | TP53ATMHTTDPP8DPP9 | |
| Cyclohexylamine SCHEMBL7792713 | 0.88 | TP53 (0.44) | TP53ATMHTTMAOAMAOB | |
| Benzaldehyde SCHEMBL8035694 | 0.88 | KIF11 (0.42) | KIF11KMT2AMEN1PPARGPPARA | |
| 3-Hydroxybenzaldehyde SCHEMBL8039117 | 0.87 | KYNU (0.40) | KIF11KMT2AMEN1GAAUNG | |
| 3-Hydroxybenzaldehyde SCHEMBL8039109 | 0.87 | KYNU (0.40) | KIF11KMT2AMEN1GAAUNG | |
| Cyclohexylamine SCHEMBL8037697 | 0.87 | GRIK1 (0.41) | KIF11NPC1RAB9AKMT2ASMN1; SMN2 | |
| Cyclohexylamine SCHEMBL8037696 | 0.87 | GRIK1 (0.41) | KIF11NPC1RAB9AKMT2ASMN1; SMN2 | |
| 3-Formylbenzoic Acid SCHEMBL8035774 | 0.86 | UNG (0.54) | UNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |