Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040593 | 0.91 | TSHR (0.47) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4009023 | 0.87 | DPP4 (0.42) | TSHRALDH1A1LMNASMN1; SMN2ADORA3 | |
| SCHEMBL4014162 | 0.82 | TSHR (0.38) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8040651 | 0.79 | ADORA3 (0.47) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4009025 | 0.79 | ACP1 (0.38) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8041719 | 0.79 | TSHR (0.59) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8030010 | 0.76 | RXRA (0.47) | TSHRALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8036828 | 0.76 | ADORA3 (0.44) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8038540 | 0.75 | GCGR (0.45) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8038586 | 0.73 | ALDH1A1 (0.45) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |