Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043331 | 0.86 | MAPT (0.34) | MAPTKDM4ECXCR3MEN1LMNA | |
| SCHEMBL8044629 | 0.83 | ALDH1A1 (0.39) | MAPTKDM4ELMNAKMT2AHTT | |
| SCHEMBL8032798 | 0.82 | KDM4E (0.32) | MAPTKDM4EHTTPAX8PIP4K2C | |
| SCHEMBL8043842 | 0.82 | KMT2A (0.44) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL8044497 | 0.82 | HTT (0.33) | MAPTKDM4ECXCR3MEN1KMT2A | |
| SCHEMBL8048290 | 0.80 | MAPT (0.35) | MAPTKDM4ECXCR3MEN1KMT2A | |
| SCHEMBL8046511 | 0.80 | HTT (0.45) | MAPTMEN1LMNAKMT2AF2RL3 | |
| SCHEMBL8044269 | 0.79 | ALDH1A1 (0.34) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL8043200 | 0.79 | ALDH1A1 (0.43) | MAPTKDM4ELMNAKMT2AHTT | |
| SCHEMBL8050841 | 0.78 | ALDH1A1 (0.37) | MAPTKDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |