Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 10/20 | 0.45 |
| ▸ | PIP4K2C | Q8TBX8 | 9/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045256 | 0.86 | MAPT (0.35) | HTTPIP4K2CPAX8MAPTF2RL3 | |
| SCHEMBL8048290 | 0.86 | MAPT (0.35) | HTTPIP4K2CPAX8MAPTF2RL3 | |
| SCHEMBL8044430 | 0.85 | CTSS (0.34) | HTTPIP4K2CPAX8MAPTF2RL3 | |
| SCHEMBL8032734 | 0.85 | ALDH1A1 (0.37) | HTTPIP4K2CPAX8MAPTF2RL3 | |
| SCHEMBL8043192 | 0.83 | ALDH1A1 (0.35) | HTTPIP4K2CPAX8MAPTDCUN1D1 | |
| SCHEMBL8047810 | 0.81 | CYP2C9 (0.37) | HTTPIP4K2CPAX8MAPTF2RL3 | |
| SCHEMBL8043614 | 0.81 | DCUN1D1 (0.41) | DCUN1D1UBE2M | |
| SCHEMBL8043200 | 0.81 | ALDH1A1 (0.43) | HTTMAPTTDP1DCUN1D1UBE2M | |
| SCHEMBL8043093 | 0.81 | SMN1; SMN2 (0.38) | MAPTTDP1F2RL3L3MBTL1ALOX5 | |
| SCHEMBL8042227 | 0.81 | MAPT (0.39) | MAPTTDP1F2RL3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |