Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033920 | 0.86 | HTT (0.49) | GPR84SSTR4SSTR1SSTR3HTT | |
| SCHEMBL8050043 | 0.86 | MAPT (0.43) | SSTR4SSTR3HTTSMN1; SMN2KMT2A | |
| SCHEMBL8043584 | 0.85 | GPR84 (0.44) | GPR84HTTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL8045236 | 0.80 | SSTR4 (0.41) | GPR84SSTR4SSTR1SSTR3SMN1; SMN2 | |
| SCHEMBL8033626 | 0.78 | KMT2A (0.42) | HTTSMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL8715778 | 0.77 | HTT (0.42) | HTTSMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL8034186 | 0.77 | MET (0.41) | GPR84SSTR4SSTR1SSTR3KMT2A | |
| SCHEMBL8050073 | 0.77 | GPR84 (0.41) | GPR84SSTR4SSTR1SSTR3HTT | |
| SCHEMBL8033967 | 0.76 | CYP1A2 (0.42) | GPR84SSTR4SSTR1SSTR3KMT2A | |
| SCHEMBL8043930 | 0.76 | KMT2A (0.44) | HTTSMN1; SMN2KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |