SCHEMBL8041944

SCHEMBL8041944

CCO[Si](CCn1c(=O)[nH]c(=O)[nH]c1=O)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PDE4A P27815 3/20 0.30
ADORA2A P29274 3/20 0.30
PDE4B Q07343 3/20 0.30
PDE4C Q08493 3/20 0.30
PDE4D Q08499 3/20 0.30
ADORA3 P0DMS8 2/20 0.30
ADORA2B P29275 2/20 0.30
HPGD P15428 1/20 0.30
ADORA1 P30542 1/20 0.30
BLM P54132 1/20 0.30
PDE3A Q14432 1/20 0.30
HSD17B10 Q99714 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GLA P06280 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4129111 0.90 ADORA2B (0.36) MEN1KMT2APDE4AADORA2APDE4B
SCHEMBL21772430 0.81 ATM (0.30)
SCHEMBL9893563 0.79 CYP1A2 (0.30) PDE4AADORA2APDE4BPDE4CPDE4D
SCHEMBL9681087 0.78 ADORA2B (0.35) MEN1KMT2APDE4AADORA2APDE4B
SCHEMBL22472307 0.77 ADORA2B (0.38) MEN1KMT2APDE4AADORA2APDE4B
SCHEMBL4126092 0.76 APEX1 (0.40) MEN1KMT2APDE4AADORA2APDE4B
SCHEMBL22472338 0.76 ADORA2B (0.40) MEN1KMT2APDE4AADORA2APDE4B
SCHEMBL29283311 0.76 DUT (0.36) MEN1KMT2AADORA2AADORA3ADORA2B
SCHEMBL29283309 0.75 PDE4A (0.31) PDE4AADORA2APDE4BPDE4CPDE4D
SCHEMBL14150299 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103465-A Coating composition, coated article, and method for forming cured film 信越化学工业株式会社 2024-05-28 CN disclosed
US-20200070481-A1 SURFACE PROTECTIVE RESIN MEMBER, MULTILAYERED RESIN MEMBER, AND SOLUTION SET FUJI XEROX CO., LTD. (JP) 2020-03-05 US disclosed
EP-0991698-A1 SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME CK WITCO CORPORATION (US) 2000-04-12 EP disclosed
WO-1999054386-A1 SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME WITCO CORPORATION (US) 1999-10-28 WO disclosed