SCHEMBL9681087

SCHEMBL9681087

CCO[Si](C)(CCCn1c(=O)[nH]c(=O)[nH]c1=O)OCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 5/20 0.35
PDE4A P27815 3/20 0.35
ADORA2A P29274 3/20 0.35
PDE4B Q07343 3/20 0.35
PDE4C Q08493 3/20 0.35
PDE4D Q08499 3/20 0.35
ADORA3 P0DMS8 3/20 0.35
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
BRD3 Q15059 1/20 0.31
BRDT Q58F21 1/20 0.31
TSHR P16473 1/20 0.31
KDM4E B2RXH2 4/20 0.31
GAA P10253 2/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29283325 0.88 ADORA2B (0.37) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL4129111 0.85 ADORA2B (0.36) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL28429834 0.83 PDE4A (0.34) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL2502693 0.81 RGS4 (0.32) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL8041944 0.78 MEN1 (0.32) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL29283309 0.77 PDE4A (0.31) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL22472307 0.76 ADORA2B (0.38) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL21816952 0.76 ADORA2B (0.39) ADORA2BADORA2AADORA3ATMALDH1A1
SCHEMBL22472338 0.75 ADORA2B (0.40) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL26034564 0.75 ADRA1D (0.35) ADORA2BPDE4AADORA2APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116271262-A Full-degradable composite barrier membrane for guiding bone regeneration 南京工程学院 2023-06-23 CN claimed
CN-113501931-B Solvent-free low-viscosity isocyanate composition and preparation method and application thereof 万华化学集团股份有限公司 2022-07-12 CN claimed
CN-113501931-A Solvent-free low-viscosity isocyanate composition and preparation method and application thereof 万华化学集团股份有限公司 2021-10-15 CN claimed
CN-118103465-A Coating composition, coated article, and method for forming cured film 信越化学工业株式会社 2024-05-28 CN disclosed
CN-116271262-A Full-degradable composite barrier membrane for guiding bone regeneration 南京工程学院 2023-06-23 CN disclosed
CN-116133843-A Composition for coating laminate and grey cloth 长濑化成株式会社 2023-05-16 CN disclosed
CN-113501931-B Solvent-free low-viscosity isocyanate composition and preparation method and application thereof 万华化学集团股份有限公司 2022-07-12 CN disclosed
CN-113501931-A Solvent-free low-viscosity isocyanate composition and preparation method and application thereof 万华化学集团股份有限公司 2021-10-15 CN disclosed
EP-0520717-A1 Adhesion promoters for room temperature vulcanizable silicone compositions GENERAL ELECTRIC COMPANY (US) 1992-12-30 EP disclosed