Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.58 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404745 | 0.77 | VCAM1 (0.64) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11477482 | 0.77 | VCAM1 (0.68) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9998849 | 0.75 | TSHR (0.56) | MAPTTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL29379293 | 0.75 | TSHR (0.56) | MAPTTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL8143514 | 0.75 | VCAM1 (0.66) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL82629 | 0.75 | VCAM1 (0.66) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL17272651 | 0.74 | MAOB (0.38) | ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL2330159 | 0.74 | VCAM1 (0.64) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1343562 | 0.74 | VCAM1 (1.00) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL21885660 | 0.74 | GPR35 (0.56) | MAPTALOX15POLBHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140528-A | ALKYL PENTAFLUOROSULFANYL-SUBSTITUTED-BENZOATES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-10-31 | — | — | US | disclosed |
| US-6013805-A | USED AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5849928-A | Herbicidal isoxazole and 2-cyano-1,3-dione compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |