SCHEMBL8041987

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13928905	0.79	ALDH1A1 (0.45)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL8043209	0.78	TRPA1 (0.32)	MAPTLMNAHTTALDH1A1MEN1
	SCHEMBL13928909	0.77	GABRA1 (0.33)	TSHRMAPTLMNAKMT2APKM
	SCHEMBL5634819	0.72	NPSR1 (0.31)	—
	SCHEMBL13928924	0.72	NPSR1 (0.31)	—
	SCHEMBL26342343	0.71	ALDH1A1 (0.54)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL13351469	0.71	GRIN2D (0.50)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL22041931	0.71	GRIN2D (0.50)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL14353372	0.71	GRIN2D (0.50)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL7953362	0.69	GRIN2D (0.62)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.