Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | MC5R | P33032 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494838 | 0.85 | FBP1 (0.59) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL80423 | 0.85 | FBP1 (0.59) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL11589539 | 0.83 | POLB (0.57) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL8662853 | 0.83 | ALDH1A1 (0.63) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL29494847 | 0.83 | ALDH1A1 (0.63) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL1193945 | 0.81 | HTR1A (0.55) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL1193757 | 0.80 | FBP1 (0.54) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL11680202 | 0.80 | FBP1 (0.54) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL1193419 | 0.79 | FBP1 (0.56) | FBP1HTR1AHTR2AHTR7ALDH1A1 | |
| SCHEMBL29494839 | 0.79 | FBP1 (0.56) | FBP1HTR1AHTR2AHTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051451-B2 | Rubber composition for breaker topping and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20120285599-A1 | RUBBER COMPOSITION FOR BREAKER TOPPING AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2012-11-15 | — | — | US | disclosed |