Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027052 | 0.77 | P2RX4 (0.50) | P2RX4P2RX7POLBMEN1KMT2A | |
| SCHEMBL6094653 | 0.77 | WDR5 (0.40) | CRHR1KMT2A | |
| SCHEMBL5496929 | 0.72 | CRHR1 (0.40) | CRHR1POLBMEN1KMT2AMAPT | |
| SCHEMBL5492382 | 0.70 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL6291133 | 0.69 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL6294463 | 0.67 | CRHR1 (0.61) | CRHR1MAPTRAB9A | |
| SCHEMBL6569974 | 0.66 | PDK1 (0.62) | P2RX4P2RX7 | |
| SCHEMBL17027092 | 0.66 | P2RX4 (0.51) | P2RX4P2RX7POLBMEN1KMT2A | |
| SCHEMBL7678044 | 0.64 | MEN1 (0.40) | P2RX4P2RX7CRHR1MEN1KMT2A | |
| SCHEMBL3983979 | 0.64 | CA1 (0.55) | P2RX4P2RX7POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |