Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687220 | 0.81 | CRHR1 (0.34) | SORT1PFKFB3CRHR1EIF4A3DHODH | |
| SCHEMBL7687217 | 0.79 | CRHR1 (0.33) | MEN1KMT2ASORT1PFKFB3CRHR1 | |
| SCHEMBL7678043 | 0.76 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1CRHR1 | |
| SCHEMBL14347187 | 0.73 | RXFP1 (0.39) | MEN1KMT2AMAPTALDH1A1CRHR1 | |
| SCHEMBL7676334 | 0.73 | MAPT (0.44) | MEN1KMT2AP2RX4P2RX7MAPT | |
| SCHEMBL5437266 | 0.71 | NFKB1 (0.35) | MAPTALDH1A1CRHR1IGF1RSMN1; SMN2 | |
| SCHEMBL7680556 | 0.69 | MAPT (0.43) | KMT2AMAPTALDH1A1CRHR1IGF1R | |
| SCHEMBL7687760 | 0.69 | NPC1 (0.39) | MEN1KMT2AP2RX4P2RX7MAPT | |
| SCHEMBL7683030 | 0.68 | ALDH1A1 (0.41) | MAPTALDH1A1CRHR1LMNA | |
| SCHEMBL7682784 | 0.67 | ALDH1A1 (0.41) | MEN1KMT2AMAPTALDH1A1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |