Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PIP4K2C | Q8TBX8 | 3/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041889 | 0.83 | LMNA (0.33) | ALDH1A1HTTMAPTLMNAHSD17B10 | |
| SCHEMBL8048309 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTLMNAHSD17B10 | |
| SCHEMBL8046180 | 0.83 | L3MBTL1 (0.39) | ALDH1A1HTTMAPTLMNAMAPK1 | |
| SCHEMBL8045200 | 0.82 | ALDH1A1 (0.33) | ALDH1A1HTTMAPTLMNAHSD17B10 | |
| SCHEMBL8048098 | 0.81 | HTT (0.31) | ALDH1A1HTTMAPTLMNAHSD17B10 | |
| SCHEMBL8047517 | 0.81 | TP53 (0.34) | ALDH1A1HTTMAPTLMNAHSD17B10 | |
| SCHEMBL8043208 | 0.80 | HSD17B10 (0.36) | ALDH1A1HTTMAPTLMNAHSD17B10 | |
| SCHEMBL8047788 | 0.80 | LMNA (0.31) | ALDH1A1HTTMAPTLMNAHSD17B10 | |
| SCHEMBL8032525 | 0.79 | POLB (0.42) | ALDH1A1HTTMAPTLMNAHSD17B10 | |
| SCHEMBL8044870 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HTTMAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |