Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050920 | 0.88 | RAB9A (0.39) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL8050622 | 0.86 | MEN1 (0.40) | KDM4EMEN1KMT2ATSHRNPC1 | |
| SCHEMBL8050300 | 0.86 | KDM4E (0.40) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL8050349 | 0.85 | MAPT (0.42) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL8044219 | 0.85 | TSHR (0.38) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL8041811 | 0.84 | ALDH1A1 (0.50) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL8051692 | 0.83 | KDM4E (0.38) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL8044119 | 0.83 | PTGS2 (0.35) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL8050087 | 0.83 | KMT2A (0.40) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL8032404 | 0.82 | MEN1 (0.36) | KDM4EMEN1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |