Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SDHB | P21912 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050920 | 0.88 | RAB9A (0.39) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL8050349 | 0.86 | MAPT (0.42) | PTGS2HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL8034019 | 0.85 | HPGD (0.36) | DRD2DRD3HDAC6KMT2AMEN1 | |
| SCHEMBL8045082 | 0.85 | MEN1 (0.45) | DRD2DRD3HDAC6KMT2AMEN1 | |
| SCHEMBL8042652 | 0.83 | KDM4E (0.40) | HDAC6KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8033982 | 0.81 | KDM4E (0.50) | DRD2DRD3HDAC6KMT2AMEN1 | |
| SCHEMBL8046726 | 0.81 | RAB9A (0.41) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL8033576 | 0.79 | CXCR3 (0.31) | HTT | |
| SCHEMBL8047418 | 0.78 | KMT2A (0.38) | HDAC6KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8050622 | 0.78 | MEN1 (0.40) | HDAC6KMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |