Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047517 | 0.85 | TP53 (0.34) | MAPTKMT2AALDH1A1LMNATP53 | |
| SCHEMBL8044070 | 0.84 | MAPT (0.36) | MAPTKMT2ARECQLMEN1POLB | |
| SCHEMBL8050058 | 0.83 | KMT2A (0.36) | MAPTKMT2ARECQLMEN1POLB | |
| SCHEMBL8041899 | 0.81 | RECQL (0.49) | MAPTKMT2ARECQLMEN1POLB | |
| SCHEMBL8044357 | 0.80 | MAPK8 (0.41) | MAPTKMT2ARECQLMEN1POLB | |
| SCHEMBL8045476 | 0.80 | KMT2A (0.40) | MAPTKMT2ARECQLMEN1POLB | |
| SCHEMBL8048098 | 0.79 | HTT (0.31) | MAPTKMT2AALDH1A1LMNATP53 | |
| SCHEMBL8048309 | 0.79 | ALDH1A1 (0.52) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL8042545 | 0.78 | ALDH1A1 (0.36) | MAPTKMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL8047480 | 0.78 | ALDH1A1 (0.39) | MAPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |